The two FDA-approved vaccines made by Pfizer-BioNTech and Moderna require 2 shots to get the most protection. Be sure to make an appointment for the second dose of the vaccine within the recommended interval. After you receive the first dose, you should continue to wear a mask in public or at work and social distance. To learn more about the recommended intervals for the COVID-19 vaccines, visit the CDC FAQ on the COVID-19 vaccines.